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Search term: ONDANSETRON
NOTE: All prescription products REQUIRE A VALID PRESCRIPTION from your doctor
  ZOFRAN ODT (ondansetron)
 ZOFRAN ODT 4mg, tablet, sublingual
ZOFRAN ODT 8mg, tablet, sublingual
ONDANSETRON DISINTEGRATING TABLET - ORAL COMMON BRAND NAME(S): ZOFRAN ODTUSES FOR ZOFRAN ODT: This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting. Ondansetron belongs to a class of medications called 5-HT3 blockers.
HOW TO USE ZOFRAN ODT: This medication is dissolved on top of the tongue. It is not meant to be chewed or swallowed like other tablet forms. Dry your hands before peeling back the foil on the blister pack to remove a tablet. Do not push the tablet through the foil. Immediately after removing the tablet, place it on the tongue, where it will dissolve in seconds. After it dissolves, swallow it with saliva. Drinking a liquid is not necessary, and taking these dissolving tablets with water may increase your chance of getting a headache. To prevent nausea from chemotherapy, take this medication usually within 30 minutes before treatment begins. To prevent nausea from radiation treatment, take this medication 1 to 2 hours before the start of your treatment. To prevent nausea after surgery, take ondansetron 1 hour before the start of surgery. This medication may be taken with or without food. However, your doctor may tell you not to eat before chemotherapy, radiation, or surgery. Take any other doses as directed by your doctor. Ondansetron may be taken up to 3 times a day for 1 to 2 days after your chemotherapy or radiation treatment is finished. If you are taking this medication on a prescribed schedule, take it regularly in order to get the most benefit from it. To help you remember, take it at the same times each day. Dosage is based on your medical condition and response to therapy. The dosage for children may also be based on age and weight. In patients with severe liver problems, the usual maximum dose is 8 milligrams in 24 hours. Take this medication exactly as directed. Do not take more medication or take it more often than prescribed. Ask your doctor or pharmacist if you have questions. Inform your doctor if your condition does not improve or if it worsens.
SIDE EFFECTS OF ZOFRAN ODT: Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your doctor promptly. Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: stomach pain, muscle spasm/stiffness, vision changes (e.g., temporary loss of vision, blurred vision). Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, fainting, slow/fast/irregular heartbeat, severe dizziness. A very serious allergic reaction to this drug is unlikely, but stop taking this medication and seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS WHEN USING ZOFRAN ODT: Before taking ondansetron, tell your doctor or pharmacist if you are allergic to it; or to other 5-HT3 blockers (e.g., granisetron); or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, stomach/intestinal problems (e.g., recent abdominal surgery, ileus, swelling). This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Avoid alcohol beverages. To minimize dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. This medicine may contain aspartame. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist regarding the safe use of this medicine. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS WHEN USING ZOFRAN ODT: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first. This drug should not be used with the following medication because a very serious interaction may occur: apomorphine. If you are currently using the medication listed above, tell your doctor or pharmacist before starting ondansetron. Before using this medication, tell your doctor of all nonprescription and prescription medication you may use, especially of: tramadol. Ask your doctor or pharmacist for more details.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
MISSED DOSE: Try to take each dose at the scheduled time. If you miss a dose, take it as soon as you remember unless it is near the time for the next dose. In that case, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE FOR ZOFRAN ODT: The dissolving tablets may be stored in the refrigerator or at room temperature between 36-86 degrees F (2-30 degrees C). Store away from light and moisture. Do not store in the bathroom. Keep all medicines out of reach of children and pets. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
ZOFRAN ODT NOTES: Do not share this product with others.
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